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The use of medical marijuana continues to be an emotionally and politically charged issue. Although cannabis oil preparations have been used in medicine for millennia, the concern over the hazards of abuse resulted in the banning of their medicinal use of marijuana in the 1930s.

Only recently, bud and related compounds come back to being considered of therapeutic value. A notable compound found in marijuana or cannabis, CBD, or cannabidiol, has shown to treat a lot of ailments. Researchers believe that in light of the very low toxicity and the normally benign side effects of CBD, neglecting or denying CBD benefits and its clinical possibility is simply unacceptable.

What Is CBD?

CBD is one of over 60 compounds found in cannabis that appeal to a class of ingredients called cannabinoids. Until recently, THC (tetrahydrocannabinol) was getting most of the attention because it's the ingredient in cannabis that creates mind-altering effects in users, but CBD can also be present in high concentrations -- and also the medical world is realizing its list of medical benefits continues to grow.

CBD is the major nonpsychoactive component of Cannabis sativa. According to some 2013 study published in the British Journal of Clinical Pharmacology, CBD benefits including acting in certain experimental versions as an anti inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic and anti inflammatory agent, and is consequently a possible medicine for treating neuroinflammation, epilepsy, cognitive injury, nausea and vomiting, schizophrenia and anxiety.

Research is beginning to show that CBD is different than other well-studied cannabinoids. Each of cannabinoids act as ligands, meaning they dock onto the binding site of a protein and have the capability to regulate a receptor's behavior. CB1 receptors are widely dispersed, but are particularly abundant in areas of the brain, such as those concerned with motion, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine functions.

CB2 receptors are found mostly in the immune system, and they appear to decrease inflammation and certain kinds of pain. Although cannabinoids have similar structures, they exhibit a wide array of activities at each of the different receptors.

However, scientists have been finding out that CBD has very little effect on CB1 and CB2 receptors, which likely explains why it doesn't have mind-altering consequences, unlike THC, which positively regulates the CB1 receptor. That is why most marijuana grown for recreational functions are typically very low in CBD and high in THC.

Proven Benefits of CBD

1. Relieves Pain and Inflammation - Among ordinary CBD advantages, natural pain relief tops the list for all. Evidence suggests that cannabinoids may prove useful in pain modulation by preventing neuronal transmission in pain pathways. A 2012 study published in the Journal of Experimental Medicine discovered that CBD significantly suppressed chronic inflammatory and neuropathic pain in rodents without causing analgesic tolerance. Researchers suggest that CBD and other nonpsychoactive components of marijuana may represent a novel class of therapeutic agents for treating chronic pain.

2. Has Antipsychotic Effects - Research indicates that CBD advantages include generating antipsychotic effects. It seems to have a pharmacological profile similar to that of atypical antipsychotic medication as seen with behavioral and neurochemical techniques in animal studies. Additionally, studies show that CBD prevents human experimental psychosis and can be effective in receptive case reports and clinical trials in patients with schizophrenia, with a remarkable safety profile.

3. Reduces Anxiety - Studies using animal models of stress and between healthy volunteers clearly suggest an anxiolytic-like impact of CBD. Cannabidiol has shown to decrease anxiety in individuals with social anxiety disorder and researchers suggest that it may also be effective for anxiety disorder, obsessive compulsive disorder, social anxiety disorder and post-traumatic anxiety disorder.

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